Current microbiology. 2023 Apr 19;80(5):188. doi: 10.1007/s00284-023-03294-0 Q32.62025

Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin

H1N1甲型流感病毒血凝素异嗜性表位的鉴定翻译改进

Jing-Ying Sun^{1 2}, Chun-Yan Guo^{1 2}, Guo-Rong Wang³, Li-Ting Yan^{1 2}, Qing Feng^{1 2}, Yan Li^{1 2}, Xue-Ping Huo^{1 2}, Xin Xie⁴, Jun Hu^{5 6}, Li-Jun Sun^{7 8}

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作者单位

¹ Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China.

² Shaanxi Province Research Center of Cell Immunological Engineering and Technology, Xi'an, 710068, Shaanxi, China.

³ General Surgery Department of Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China.

⁴ Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, 710069, Shaanxi, China.

⁵ Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China. hujun_1112@126.com.

⁶ Shaanxi Province Research Center of Cell Immunological Engineering and Technology, Xi'an, 710068, Shaanxi, China. hujun_1112@126.com.

⁷ Shaanxi Provincial Key Laboratory of Infection and Immune Diseases, Shaanxi Provincial People's Hospital, Xi'an, 710068, Shaanxi, China. lijun200206@163.com.

⁸ Shaanxi Province Research Center of Cell Immunological Engineering and Technology, Xi'an, 710068, Shaanxi, China. lijun200206@163.com.

DOI: 10.1007/s00284-023-03294-0 PMID: 37074450

摘要 Ai翻译

Our previous studies found that the H1-50 monoclonal antibody (mAb) of influenza A virus hemagglutinin (HA) cross-reacted with pancreatic tissue and islet β-cells, and further studies showed that H1-50 mAb binds to prohibitin (PHB) protein of islet β-cells. These suggest that there are heterophilic epitopes between influenza virus HA and pancreatic tissue, which may be involved in the pathogenesis of type 1 diabetes. To further investigate these heteroph... ...点击完成人机验证后继续浏览

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期刊名：Current microbiology

缩写：CURR MICROBIOL

ISSN：0343-8651

e-ISSN：1432-0991

IF/分区：2.6/Q3

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Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin

H1N1甲型流感病毒血凝素异嗜性表位的鉴定翻译改进

Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin

含有H5N1血凝素的2009年甲型H1N1流感病毒重配株致病性增强

Antibodies against H1N1 influenza virus hemagglutinin cross-react with prohibitin

针对甲型H1N1流感病毒血凝素的抗体与 prohibitin 交叉反应

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions

甲型H1N1流感病毒HA蛋白的进化：通过补偿性突变来保持最佳受体结合能力

The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice

猪流感病毒血凝素蛋白中的S190R突变增加了其致病性

Characterization of an enhanced antigenic change in the pandemic 2009 H1N1 influenza virus haemagglutinin

2009大流行H1N1流感病毒血凝素抗原改变的表征

Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model

甲型H1N1流感病毒血凝素S110L突变体在小鼠模型中的潜在减毒表型研究

Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance

基于大流行性H1N1（2009）流感病毒重组血凝素蛋白的酶联免疫吸附测定法的应用价值评价研究

Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus

血凝素裂解位点的改变调控神经毒型H1N1流感病毒的毒力

Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin

H1N1甲型流感病毒血凝素异嗜性表位的鉴定 翻译改进

Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutinin

含有H5N1血凝素的2009年甲型H1N1流感病毒重配株致病性增强

Antibodies against H1N1 influenza virus hemagglutinin cross-react with prohibitin

针对甲型H1N1流感病毒血凝素的抗体与 prohibitin 交叉反应

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions

甲型H1N1流感病毒HA蛋白的进化：通过补偿性突变来保持最佳受体结合能力

The S190R mutation in the hemagglutinin protein of pandemic H1N1 2009 influenza virus increased its pathogenicity in mice

猪流感病毒血凝素蛋白中的S190R突变增加了其致病性

Characterization of an enhanced antigenic change in the pandemic 2009 H1N1 influenza virus haemagglutinin

2009大流行H1N1流感病毒血凝素抗原改变的表征

Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model

甲型H1N1流感病毒血凝素S110L突变体在小鼠模型中的潜在减毒表型研究

Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance

基于大流行性H1N1（2009）流感病毒重组血凝素蛋白的酶联免疫吸附测定法的应用价值评价研究

Modifications to the hemagglutinin cleavage site control the virulence of a neurotropic H1N1 influenza virus

血凝素裂解位点的改变调控神经毒型H1N1流感病毒的毒力

H1N1甲型流感病毒血凝素异嗜性表位的鉴定翻译改进