A Twist-Box domain of the C. elegans Twist homolog, HLH-8, plays a complex role in transcriptional regulation
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TWIST1 is a basic helix-loop-helix (bHLH) transcription factor in humans that functions in mesoderm differentiation. TWIST1 primarily regulates genes as a transcriptional repressor often through TWIST-Box domain-mediated protein-protein interactions. The TWIST... ...