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International journal of molecular sciences. 2023 Apr 5;24(7):6775. doi: 10.3390/ijms24076775 Q14.92024

Machine Learning as a Support for the Diagnosis of Type 2 Diabetes

机器学习在2型糖尿病诊断中的应用支持 翻译改进

Antonio Agliata  1  2, Deborah Giordano  3, Francesco Bardozzo  1, Salvatore Bottiglieri  2, Angelo Facchiano  3, Roberto Tagliaferri  1

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作者单位

  • 1 Dipartimento di Scienze Aziendali, Management and Innovation Systems, Università degli Studi di Salerno, 84084 Fisciano, Italy.
  • 2 BC Soft, Centro Direzionale, Via Taddeo da Sessa Isola F10, 80143 Napoli, Italy.
  • 3 National Research Council, Institute of Food Science, Via Roma 64, 83100 Avellino, Italy.
  • DOI: 10.3390/ijms24076775 PMID: 37047748

    摘要 Ai翻译

    Diabetes is a chronic, metabolic disease characterized by high blood sugar levels. Among the main types of diabetes, type 2 is the most common. Early diagnosis and treatment can prevent or delay the onset of complications. Previous studies examined the application of machine learning techniques for prediction of the pathology, and here an artificial neural network shows very promising results as a possible valuable aid in the management and prevention of diabetes. Additionally, its superior ability for long-term predictions makes it an ideal choice for this field of study. We utilized machine learning methods to uncover previously undiscovered associations between an individual's health status and the development of type 2 diabetes, with the goal of accurately predicting its onset or determining the individual's risk level. Our study employed a binary classifier, trained on scratch, to identify potential nonlinear relationships between the onset of type 2 diabetes and a set of parameters obtained from patient measurements. Three datasets were utilized, i.e., the National Center for Health Statistics' (NHANES) biennial survey, MIMIC-III and MIMIC-IV. These datasets were then combined to create a single dataset with the same number of individuals with and without type 2 diabetes. Since the dataset was balanced, the primary evaluation metric for the model was accuracy. The outcomes of this study were encouraging, with the model achieving accuracy levels of up to 86% and a ROC AUC value of 0.934. Further investigation is needed to improve the reliability of the model by considering multiple measurements from the same patient over time.

    Keywords: T2DM; artificial intelligence; neural network.

    Keywords:machine learning; type 2 diabetes; diagnosis support

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    期刊名:International journal of molecular sciences

    缩写:INT J MOL SCI

    ISSN:1661-6596

    e-ISSN:1422-0067

    IF/分区:4.9/Q1

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    Machine Learning as a Support for the Diagnosis of Type 2 Diabetes