Cu(I)-azidopyrrolo[3,2- d]pyrimidine Catalyzed Glaser-Hay Reaction under Mild Conditions
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The limitation of the CuAAC "click" reaction with a 2-azidopyridine substrate, owing to its equilibrium with a tetrazole isomer, is exploited herein for its utility in the Glaser-Hay reaction. A catalytic combination of a 2-azidopyridine analogue, 4-azido-5H-p... ...