Structural Elucidation of Ivermectin Binding to α7nAChR and the Induced Channel Desensitization
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The α7 nicotinic acetylcholine receptor (α7nAChR) mediates signaling in the central nervous system and cholinergic anti-inflammatory pathways. Ivermectin is a positive allosteric modulator of a full-length α7nAChR and an agonist of the α7nAChR construct co... ...
