Objectives: During the 18th and 19th centuries, many books about science were published. Constantinos Michael (1751-1816), the first medical historian to write in Greek, contributed to this literature. Born in Kastoria, Greece, Constantinos Michael lived and studied medicine and philosophy in Vienna. His book Dietetics describes how lifestyle and diet can benefit or harm human health. Though not well known, Constantinos Michael made substantial contributions to medical scholarship and the promotion of Greek history and Hellenic culture, as described in this study. This is the first such study of Constantinos Michael and his medical treatise, Dietetics.