Age-related changes in excitatory and inhibitory intra-cortical circuits in auditory cortex of C57Bl/6 mice
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A common impairment in aging is age-related hearing loss (presbycusis), which manifests as impaired spectrotemporal processing. Aging is accompanied by alteration in normal inhibitory (GABA) neurotransmission, and changes in excitatory (NMDA and AMPA) synapses... ...