LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens
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Celiac disease (CeD) is an autoimmune disorder in which gluten-derived antigens trigger inflammation. Antigenic peptides must undergo site-specific deamidation to be presentable to CD4+ T cells in an HLA-DQ2 or -DQ8 restricted manner. While the biochemical bas... ...
