Parkinson's disease-associated 18 bp promoter variant of DJ-1 alters REST binding and regulates its expression
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Parkinson's disease (PD) is a progressive neurodegenerative disorder with a complex etiology. Presence of autosomal mutations in PARK7/DJ-1 gene has been associated with early-onset PD. Growing evidence has suggested that DJ-1 acts as a putative sensor of oxid... ...
