Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation
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Degenerative mitral valve (MV) regurgitation (MR) is a highly prevalent heart disease that requires surgery in severe cases. Here, we show that a decrease in the activity of the serotonin transporter (SERT) accelerates MV remodeling and progression to MR. Thro... ...
