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Objective:The purpose of this study was to investigate the clinical characteristics and risk factors of adult recurrent acute infectious epiglottitis. Methods:All patients diagnosed with acute infectious epiglottitis hospitalized in the Department of Otolaryngology, Hai'an People's Hospital, Nantong University from January 2012 to December 2019 were included. Results:The recurrence rate of 331 adult patients with acute infectious epiglottitis was 4.2% （14/331）, including 10 cases of once recurrence and 4 cases of twice recurrence. The onset time of all patients was within 48 hours. The most common main complaint in the recurrent group was sore throat （42.9%）, and dysphagia in the non-recurrent group （42.0%）. The frequency of drinking in recurrent group was higher than that in non-recurrent group （P=0.009）. The incidence of chronic obstructive pulmoriary disease（COPD）, diabetes, cyst and gastroesophageal reflux disease/laryngopharyngeal reflux disease in recurrent group was higher than that in non-recurrent group. There was no significant difference in other clinical features, treatment and prognosis between the two groups except tongue tonsil infection under laryngoscope. Multivariate analysis showed that frequent drinking （more than twice a week）, COPD, diabetes, cysts and lingual tonsillar infection were the risk factors for recurrence. Conclusion:Adult acute infectious epiglottitis has a proportion of single or multiple recurrence. Frequent drinking, COPD, diabetes, cyst and lingual tonsillar infection are the risk factors for the recurrence.
目的：探讨成人急性感染性会厌炎复发的临床特征和危险因素。 方法：回顾性分析2012年1月—2019年12月在南通大学附属海安医院耳鼻咽喉科住院及门急诊治疗的成人急性感染性会厌炎患者的相关资料。 结果：331例成人急性感染性会厌炎患者的复发率为4.2%（14/331），其中10例复发1次，4例复发2次。所有患者起病时间均在48 h以内，复发组最常见的主诉为咽喉疼痛（42.9%），非复发组为吞咽困难（42.0%）。复发组的饮酒频率高于非复发组（P=0.009）。复发组慢性阻塞性肺疾病（COPD）、糖尿病、会厌囊肿和胃食管反流疾病/咽喉反流疾病的发生率高于非复发组。除喉镜下舌扁桃体感染外，两组在其他临床特征、治疗和预后方面均无显著差异。多变量分析表明，经常饮酒（≥2次/周）、COPD、糖尿病、会厌囊肿和舌扁桃体感染是成人急性感染性会厌炎复发的危险因素。 结论：成人急性感染性会厌炎有一定比例会单次或多次复发，经常饮酒、COPD、糖尿病、会厌囊肿和舌扁桃体感染是急性感染性会厌炎复发的危险因素。.
Keywords: acute epiglottitis; clinical features; recurrence; risk factors.
Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.