Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey
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With the ultimate goal of developing a more representative animal model of Alzheimer's disease (AD), two female amyloid-β-(Aβ) precursor protein-transgenic (APPtg) rhesus monkeys were generated by lentiviral transduction of the APP gene into rhesus oocytes, ... ...