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Imaginal disk growth factors are Drosophila chitinase-like proteins with roles in morphogenesis and CO2 response

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Chitinase-like proteins (CLPs) are members of the family 18 glycosyl hydrolases, which include chitinases and the enzymatically inactive CLPs. A mutation in the enzyme's catalytic site, conserved in vertebrates and invertebrates, allowed CLPs to evolve indepen... ...