首页 文献索引 SCI期刊 AI助手
首页 正文

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 2023 Apr;25(4):717-727. doi: 10.1111/codi.16447 Q32.92024

Leukopenia is an independent risk factor for early postoperative complications following incision and drainage of anorectal abscess

leukopenia是肛门直肠脓肿切开引流术后早期并发症的独立危险因素 翻译改进

Mustafa Tamim Alam Khan  1, Ronit Patnaik  1, Jian Yu Huang  2, Haisar Dao Campi  1, Lisandro Montorfano  3, Felice De Stefano  4, Raul J Rosenthal  3, Steven D Wexner  4

作者单位 +展开

作者单位

  • 1 Department of Surgery, University of Texas Health San Antonio, San Antonio, Texas, USA.
  • 2 Long School of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.
  • 3 Department of Minimally Invasive Surgery, Cleveland Clinic Florida, Weston, Florida, USA.
  • 4 Ellen Leifer Shulman and Steven Shulman Digestive Disease Center, Cleveland Clinic Florida, Weston, Florida, USA.

    • DOI: 10.1111/codi.16447 PMID: 36550093

    摘要 Ai翻译

    Aim: Few data are available regarding the management of anorectal abscess in patients with leukopenia. The aim of this study was to investigate the impact of leukopenia among patients undergoing incision and drainage for anorectal abscess.

    Method: A retrospective review of the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database identified patients from 2015 to 2020. Perianal fistulas and supralevator abscesses were excluded. Patients were grouped based on white blood cell (WBC) count: WBC < 4.5 cells/μl, WBC = 4.5-11.0 cells/μl and WBC > 11.0 cells/μl. The 30-day overall complications and outcomes were compared using regression models, accounting for demographics and comorbidities.

    Results: Ten thousand two hundred and forty (70.3% male) patients were identified. Univariate analysis showed that, compared with patients with leukocytosis (WBC > 11.0 cells/μl) and normal WBC count (WBC = 4.5-11.0 cells/μl), patients with leukopenia (WBC <4.5 cells/μl) had higher rates of overall (p < 0.001), pulmonary (p < 0.001) and haematological complications (p < 0.001). They also had higher rates of readmission (p < 0.001), reoperation (p = 0.005), discharge to a care facility (p = 0.003), increased length of hospital stay (p = 0.004) and death (p < 0.001). Multivariable analysis identified leukopenia as an independent risk factor for overall complications [odds ratio (OR) 2.31, 95% CI 1.65-3.24; p < 0.001], pulmonary complications (OR 5.65, 95% CI 1.88-16.97; p = 0.002), haematological complications (OR 4.30, 95% CI 2.94-6.28; p < 0.001), unplanned readmission (OR 2.20, 95% CI 1.43-3.40; p < 0.001), reoperation (OR 1.80, 95% CI 1.10-2.93; p = 0.019) and death (OR 2.77, 95% CI 1.02-7.52; p = 0.046). Discharge to a care facility and length of stay were not significant on multivariable analysis.

    Conclusion: Leukopenia is associated with increased risk for pulmonary and haematological complications, readmissions, reoperations, discharge to a care facility and death after incision and drainage for anorectal abscess.

    Keywords: anorectal abscess; early postoperative complication; incision and drainage; leukopenia; risk factor.

    Keywords：Leukopenia; independent risk factor; incision and drainage; anorectal abscess

    关键词：白细胞减少症; 独立危险因素; 早期术后并发症; 切开引流; 肛门直肠脓肿

    Copyright © Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 中文内容为AI机器翻译，仅供参考！

    相关内容

    期刊名：Colorectal disease

    缩写：COLORECTAL DIS

    ISSN：1462-8910

    e-ISSN：1463-1318

    IF/分区：2.9/Q3

    文章目录 更多期刊信息

    全文链接
    官方链接
    PMC全文
    引文链接
    复制
    已复制！
    推荐内容
    Leukopenia is an independent risk factor for early postoperative complications following incision and drainage of anorectal abscess