A High-Throughput Fluorescence Polarization-Based Assay for the SH2 Domain of STAT4
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The signal transducer and activation of transcription (STAT) proteins are a family of Src homology 2 (SH2) domain-containing transcription factors. The family member STAT4 is a mediator of IL-12 signalling and has been implicated in the pathogenesis of multipl... ...