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Critical roles of linker length in determining the chemical and self-assembly stability of SN38 homodimeric nanoprodrugs

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Homodimeric prodrug nanoassemblies (HDPNs) have been widely studied for efficient cancer therapy by virtue of their ultra-high drug loading and distinct nanostructure. However, the development of SN38 HDPNs is still a great challenge due to the rigid planar ar... ...