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Upregulated TSP1 and CD47 expression in the lung in nitrofen-induced congenital diaphragmatic hernia

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Background: Persistent pulmonary hypertension remains a major cause of mortality and morbidity in congenital diaphragmatic hernia (CDH). The secreted glycoprotein thrombospondin-1 (TSP1), a ligand for receptor CD47, is widely exp... ...