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An electrochemiluminescence assay for quantification of Denileukin Diftitox and its anti-drug antibodies in rat serum

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Denileukin Diftitox (DD), comprising fragments of diphtheria toxin (DT) and interleukin-2 (IL2), was developed for the treatment of lymphoma and has been approved for marketing in Japan. Toxicological evaluation including pharmacokinetics and immunogenicity in... ...