Deficiency in TLR4 impairs regulatory B cells production induced by Schistosome soluble egg antigen
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Regulatory B cells (Bregs) producing IL-10 have negative regulatory function. Several studies have shown the important roles for Toll-like receptor 2 (TLR2), TLR4, and TLR9 ligation in the development of Bregs. We have reported that Schistosome soluble egg ant... ...