Interleukin-3 stabilizes CD124/IL-4α surface expression in mast cells via Tyk2 and STAT6
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Interleukin (IL)-4 signals can modulate mast cells, which express the IL-4Rα chain. The IL-4Rα can heterodimerise with the common γ-chain and utilizes JAK1 and JAK2 for signal transduction, while complexes of IL-4Rα with IL-13Rα1 subunit mediates signals ... ...
