Construction and heterologous expression of the di-AFN A1 biosynthetic gene cluster in Streptomyces model strains
{{output}}
Natural cyclohexapeptide AFN A1 fromStreptomyces alboflavus 313 has moderate antibacterial and antitumor activities. An artificial designed AFN A1 homodimer, di-AFN A1, is an antibiotic exhibiting 10 to 150 fold higher biological activities, compared with the ... ...
