Dramatic Response After Switching MEK Inhibitors in a Patient With Refractory Mixed Histiocytosis
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We report the case of a patient with progressive multisystem mixed histiocytosis associating Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) involving the bone marrow, whose lesions harbored the MAP2K1 E102-I103del. After initial improvem... ...
