Application of mevalonolactone prevents deterioration of epidermal barrier function by accelerating the lamellar granule lipid transport system
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Background: Fatty acids increase ATP-binding cassette ABC transporter A12 (ABCA12) levels via an increase in peroxisome proliferator-activated receptor β/δ (PPAR β/δ). Promoting lipid transport to lamellar granules has been s... ...