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Localized PD-1 Blockade in a Mouse Model of Renal Cell Carcinoma

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Herein we report the impact of localized delivery of an anti-mouse PD-1-specific monoclonal antibody (aPD1) on Renca tumors in the resulting T cell responses and changes in broader immune gene expression profiles. Renca is a BALB/c mice syngeneic tumor that ha... ...