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Lactoferrin-derived chimeric peptide (LFch) strongly boosts TGFβ1-mediated inducible Treg differentiation possibly through downregulating TCR/CD28 signalling

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We recently reported that lactoferrin (LF) induces Foxp3+ Treg differentiation through binding to TGFβ receptor III (TβRIII), and this activity was further enhanced by TGFβ1. Generally, a low T-cell receptor (TCR) signal strength is favourable for Foxp3+ Tr... ...