A LRRK2/dLRRK-mediated lysosomal pathway that contributes to glial cell death and DA neuron survival
{{output}}
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial and sporadic Parkinson's disease. A plethora of evidence has indicated a role for LRRK2 in endolysosomal trafficking in neurons, while LRRK2 function in glia, although high... ...
