The structure-specific endonuclease complex SLX4-XPF regulates Tus-Ter-induced homologous recombination
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Vertebrate replication forks arrested at interstrand DNA cross-links (ICLs) engage the Fanconi anemia pathway to incise arrested forks, 'unhooking' the ICL and forming a double strand break (DSB) that is repaired by homologous recombination (HR). The FANCP pro... ...
