USP12 positively regulates M-MDSC function to inhibit antitumour immunity through deubiquitinating and stabilizing p65
{{output}}
The relative abundance of myeloid-derived suppressor cells (MDSCs) compared to cytotoxic T cells determines the outcomes of diseases and the efficacy of immunotherapy. Ubiquitin-specific peptidase 12 (USP12), a member of the USP family of deubiquitinases, targ... ...
