Delay of endothelial cell senescence protects cerebral barrier against age-related dysfunction: role of senolytics and senomorphics
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Accumulation of senescent cells in cerebrovasculature is thought to play an important role in age-related disruption of blood-brain barrier (BBB). Using an in vitro model of human BBB, composed of brain microvascular endothelial cells (BMECs), astrocytes and p... ...