Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function
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Reactive oxygen species (ROS) have been implicated as mediators of pancreatic β-cell damage. While β-cells are thought to be vulnerable to oxidative damage, we have shown, using inhibitors and acute depletion, that thioredoxin reductase, thioredoxin, and per... ...
