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The role of BAG3 in dilated cardiomyopathy and its association with Charcot-Marie-Tooth disease type 2

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Bcl2-associated athanogene 3 (BAG3) is a multifunctional cochaperone responsible for protein quality control within cells. BAG3 interacts with chaperones HSPB8 and Hsp70 to transport misfolded proteins to the Microtubule Organizing Center (MTOC) and degrade th... ...