The CBP-1/p300 Lysine Acetyltransferase Regulates the Heat Shock Response in C. elegans
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The decline of proteostasis is a hallmark of aging that is, in part, affected by the dysregulation of the heat shock response (HSR), a highly conserved cellular response to proteotoxic stress in the cell. The heat shock transcription factor HSF-1 is well-studi... ...
