Virtual drug repurposing study for the CGRPR identifies pentagastrin and leuprorelin as putative candidates
{{output}}
Calcitonin gene-related peptide receptor (CGRPR) is a heterodimer consisting of CLR and RAMP1 proteins. Activation of the CGRPR with the endogenous peptide CGRP is known to play a crucial role in migraine pathophysiology. CGRP occupies two regions in the CGRPR... ...
