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Case Reports Hepatology forum. 2021 Sep 7;2(3):112-116. doi: 10.14744/hf.2021.2021.0010 Q32.12025

A novel insight into the pathophysiology of autoimmune hepatitis: An immune activator mutation in the FLT3 receptor

自身免疫性肝炎病理生理的新见解:FLT3受体上的免疫激活突变 翻译改进

Muhammed Yuksel  1  2, Ayse Armutlu  3, Farinaz Nazmi  1  2, Serdar Ceylaner  4, Cigdem Arikan  1  2

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作者单位

  • 1 Paediatric Gastroenterology-Hepatology/Liver Transplantation Centre, Koc University, Istanbul, Turkey.
  • 2 Research Centre for Translational Medicine (KUTTAM)-Liver Immunology Laboratory, Koc University, Istanbul, Turkey.
  • 3 Department of Pathology, Koc University Hospital, Istanbul, Turkey.
  • 4 Intergen Diagnostic Centre for Genetic Disorders, Ankara, Turkey.
  • DOI: 10.14744/hf.2021.2021.0010 PMID: 35784907

    摘要 Ai翻译

    Autoimmune hepatitis (AIH) is a chronic progressive autoimmune liver disease characterized by hypergammaglobulinemia, interface hepatitis, a female preponderance, and the presence of autoantibodies in most patients. The presence of HLA-DR3/DR4 and functional impairment in regulatory T cells are associated with AIH. However, AIH is a multifactorial complex disease. This report is a description of a case of seronegative AIH in a girl with chronic hepatitis, ... ...点击完成人机验证后继续浏览
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    期刊名:Hepatology forum

    缩写:HEPATOL FORUM

    ISSN:1307-5888

    e-ISSN:2757-7392

    IF/分区:2.1/Q3

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    A novel insight into the pathophysiology of autoimmune hepatitis: An immune activator mutation in the FLT3 receptor