Abelson tyrosine kinase controls BCR signalling and B-cell differentiation by promoting B-cell metabolism
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As a nonreceptor tyrosine kinase, Abelson tyrosine kinase (c-Abl) was first studied in chronic myelogenous leukaemia, and its role in lymphocytes has been well characterised. c-Abl is involved in B-cell development and CD19-associated B-cell antigen receptor (... ...