Both prokaryotes and eukaryotes produce an immune response against plasmids with 5'-GTTTGTT-3'
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In the evolutionary "arms race" from prokaryotes to eukaryotes, some memories of foreign DNA have been conserved for defensive purposes. Shortly after invasion by the plasmid, pEGFP-N1, the conserved the defense gene, isg15, was activated in the zebrafish zygo... ...
