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Crystallization of ApoA1 and ApoE4 nanolipoprotein particles and initial XFEL-based structural studies

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Nanolipoprotein particles (NLPs), also called "nanodiscs", are discoidal particles with a patch of lipid bilayer corralled by apolipoproteins. NLPs have long been of interest due to both their utility as membrane-model systems into which membrane proteins can ... ...