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Effect of the R126C mutation on the structure and function of the glucose transporter GLUT1: A molecular dynamics simulation study

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Glucose transporter 1 (GLUT1) is responsible for basal glucose uptake and is expressed in most tissues under normal conditions. GLUT1 mutations can cause early-onset absence epilepsy and myoclonus dystonia syndrome (MDS), with MDS potentially lethal. In this s... ...