A yeast suppressor screen links Coa4 to the mitochondrial copper delivery pathway for cytochrome c oxidase
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Cytochrome c oxidase (CcO) is a multimeric copper-containing enzyme of the mitochondrial respiratory chain that powers cellular energy production. The two core subunits of cytochrome c oxidase, Cox1 and Cox2, harbor the catalytic CuB and CuA sites, respectivel... ...