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Dendritic cells can prime anti-tumor CD8+ T cell responses through major histocompatibility complex cross-dressing

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Antigen cross-presentation, wherein dendritic cells (DCs) present exogenous antigen on major histocompatibility class I (MHC-I) molecules, is considered the primary mechanism by which DCs initiate tumor-specific CD8+ T cell responses. Here, we demonstrate that... ...