Constructing conformational library for amyloid-β42 dimers as the smallest toxic oligomers using two CHARMM force fields
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The study of amyloid-β (Aβ) dimers as the smallest toxic aggregates in the human brain suffering from Alzheimer's disease is of great interest. The structural characterization of the dimers, which is important to rationally design inhibitors for Aβ dimeriza... ...