Inosine monophosphate dehydrogenase type1 sustains tumor growth in hepatocellular carcinoma
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Background: Inosine monophosphate dehydrogenase (IMPDH) is the key enzyme in the biosynthesis of purine nucleotides. IMPDH1 and IMPDH2 are the two isoforms of IMPDH and they share 84% amino acid similarity and virtually indisting... ...
