Aza-Heterocycles via Copper-Catalyzed, Remote C-H Desaturation of Amines
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The majority of medicines contain a nitrogen atom within a five- or six- membered ring. To rapidly access both such aza-heterocycles, we sought to develop a remote C-H desaturation of amines. Inspired by the Hofmann-Löffler-Freytag synthesis of five-membered ... ...
