An updated patent review of small-molecule ROS1 kinase inhibitors (2015-2021)
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Introduction: C-ros oncogene 1 (ROS1) is the sole member of the ROS1 receptor tyrosine kinase (ROS1-RTK) family, which is involved in the formation of non-small cell lung cancer (NSCLC), gastric adenocarcinoma, colorectal cancer,... ...