[Recent advances in the structural biology of the class C G protein-coupled receptors: The metabotropic Glutamate receptor 5]
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Class C GPCRs, that include metabotropic glutamate receptors (mGlu), taste receptors, GABAB receptor and Calcium-sensing receptor, are unusual in terms of their molecular architecture and allosteric regulation. They all form obligatory dimers, dimerization bei... ...