Endothelial superoxide dismutase 2 is decreased in sickle cell disease and regulates fibronectin processing
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Sickle cell disease (SCD) is a genetic red blood cell disorder characterized by increased reactive oxygen species (ROS) and a concordant reduction in antioxidant capacity in the endothelium. Superoxide dismutase 2 (SOD2) is a mitochondrial-localized enzyme tha... ...