Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
{{output}}
Glycoprotein 2 (GP2) and uromodulin (UMOD) filaments protect against gastrointestinal and urinary tract infections by acting as decoys for bacterial fimbrial lectin FimH. By combining AlphaFold2 predictions with X-ray crystallography and cryo-EM, we show that ... ...
