SETDB1-like MET-2 promotes transcriptional silencing and development independently of its H3K9me-associated catalytic activity
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Transcriptionally silenced heterochromatin bearing methylation of histone H3 on lysine 9 (H3K9me) is critical for maintaining organismal viability and tissue integrity. Here we show that in addition to ensuring H3K9me, MET-2, the Caenorhabditis elegans homolog... ...
