Carnitine palmitoyl transferase I: Conformational changes induced by long-chain fatty acyl CoA ligands
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The Carnitine Palmitoyltranferase I (CPT1) catalyzes the rate-limiting step of long-chain fatty acid (LCFA) mitochondrial β-oxidation. The enzyme promotes the conjugation of LCFA with l-carnitine, which allows LCFA to enter the mitochondria matrix. The struct... ...