Genetic analysis argues for a coactivator function for the Saccharomyces cerevisiae Tup1 corepressor
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The Tup1-Cyc8 corepressor complex of Saccharomyces cerevisiae is recruited to promoters by DNA-binding proteins to repress transcription of genes, including the a-specific mating-type genes. We report here a tup1(S649F) mutant that displays mating irregulariti... ...
